Heart Failure Risk in Patients With Systemic Autoimmune Inflammatory Diseases

Patients with systemic sclerosis, systemic lupus erythematosus, and rheumatoid arthritis had increased risk of incident HF independent of traditional risk factors, indicating an underlying autoimmune mechanism of cardiac involvement. Beta-blocker use was associated with decreased incident HF, indicating a potentially cardioprotective effect in SAIDs.

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Publication Details

Journal
Journal of the American Heart Association
Published
2026-01-14
DOI
https://doi.org/10.1161/jaha.124.039155
Primary Topic
Rheumatoid Arthritis Research and Therapies
Type
article
Field-Weighted Citation Impact
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article

Heart Failure Risk in Patients With Systemic Autoimmune Inflammatory Diseases

Alexia Zagouras, Pieter Martens, W. H. Wilson Tang
Journal of the American Heart Association
Rheumatoid Arthritis Research and Therapies
article

Heart Failure Risk in Patients With Systemic Autoimmune Inflammatory Diseases

Alexia Zagouras, Pieter Martens, W. H. Wilson Tang
article en

Abstract

Patients with systemic sclerosis, systemic lupus erythematosus, and rheumatoid arthritis had increased risk of incident HF independent of traditional risk factors, indicating an underlying autoimmune mechanism of cardiac involvement. Beta-blocker use was associated with decreased incident HF, indicating a potentially cardioprotective effect in SAIDs.

Journal of the American Heart AssociationVol. 15(2)
Cleveland Clinic (US), Ziekenhuis Oost-Limburg (BE), Stanford University (US)
Good health and well-being
Openalex Percentile: Top 89%
Rheumatoid Arthritis Research and Therapies
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