Metabolomic identification and analysis of potential biomarkers of febrile seizures
Patients with FS exhibited a distinct metabolic profile characterized by activated necroptosis, dysregulated lipid metabolism, and inflammatory imbalance. Metabolites such as arachidonic acid, lysophosphatidylcholines, and sphingolipids may serve as potential biomarkers and therapeutic targets. This study provides new metabolomic evidence for early prediction and targeted intervention of FS.
Authors
- Xiaoyan Gao (ORCID: https://orcid.org/0000-0001-8219-1370)
- Haiting Tang
- Guilin Yuan
- Yaowen Liang
- Xiaowen Li
- Quan Yang
- Shaolun Pan
Institutions
- Foshan Maternity and Child Health Care Hospital (CN)
- Southern Medical University (CN)
Publication Details
- Journal
- BMC Pediatrics
- Published
- 2026-01-14
- DOI
- https://doi.org/10.1186/s12887-025-06497-5
- Primary Topic
- Sphingolipid Metabolism and Signaling
- Type
- article
- Field-Weighted Citation Impact
- 0.00