The Dynamics of Human Cytomegalovirus Markers in Tuberculosis Disease Among People With Human Immunodeficiency Virus on Long-term Antiretroviral Therapy: A Nested Case-Control Study

HCMV viremia and serology measured 6-24 months before TB diagnosis in cases did not differ from those in matched controls. At TB diagnosis, people with HIV with TB had higher proportion of HCMV viremia and higher GMC of HCMV IgM, possibly reflecting HCMV reactivation due to TB disease.

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Publication Details

Journal
Open Forum Infectious Diseases
Published
2025-12-26
DOI
https://doi.org/10.1093/ofid/ofag015
Primary Topic
Cytomegalovirus and herpesvirus research
Type
article
Field-Weighted Citation Impact
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article

The Dynamics of Human Cytomegalovirus Markers in Tuberculosis Disease Among People With Human Immunodeficiency Virus on Long-term Antiretroviral Therapy: A Nested Case-Control Study

Chavachol Setthaudom, Stephen John Kerr, Frank C M van Leth, Sivaporn Gatechompol et al.
Open Forum Infectious Diseases
Cytomegalovirus and herpesvirus research
article

The Dynamics of Human Cytomegalovirus Markers in Tuberculosis Disease Among People With Human Immunodeficiency Virus on Long-term Antiretroviral Therapy: A Nested Case-Control Study

Chavachol Setthaudom, Stephen John Kerr, Frank C M van Leth, Sivaporn Gatechompol, Anchalee Avihingsanon, Frank Cobelens, Sasiwimol Ubolyam, Thitiporn Somjit
article en

Abstract

HCMV viremia and serology measured 6-24 months before TB diagnosis in cases did not differ from those in matched controls. At TB diagnosis, people with HIV with TB had higher proportion of HCMV viremia and higher GMC of HCMV IgM, possibly reflecting HCMV reactivation due to TB disease.

Open Forum Infectious DiseasesVol. 13(1)
Chulalongkorn University (TH), UNSW Sydney (AU), HIV Netherlands Australia Thailand Research Collaboration (TH), Amsterdam Institute for Global Health and Development (NL), Ramathibodi Hospital (TH), Department of Health (ZA), Vrije Universiteit Amsterdam (NL)
Good health and well-being
Openalex Percentile: Top 27%
Cytomegalovirus and herpesvirus research
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