Boosting Ultra‐Sensitivity in Surface Plasmon Resonance Sensors With MXene

ABSTRACT With the ongoing advancement of modern society, the demand for high‐sensitivity and real‐time detection sensors continues to grow, thereby accelerating the development of sensing technologies. Surface plasmon resonance (SPR) sensing has emerged as a valuable technique owing to its real‐time, label‐free, and rapid detection capabilities. However, its limited sensitivity and detection range remain major challenges in optical sensing. MXenes, as two‐dimensional (2D) materials, have garnered considerable attention owing to their large specific surface area, high electrical conductivity, excellent biocompatibility, and stability, establishing them as one of the most prominent materials for optical sensing. This paper first provides a concise overview of the properties of MXenes, followed by an analysis of various SPR sensor configurations and performance improvement strategies. Finally, it summarizes the latest advances in the application of MXenes in SPR sensors, discusses their potential for enhancing sensing performance, and offers a perspective on development directions. Despite being in its early stages, MXene‐based SPR sensing has demonstrated significant potential for expanding into broader applications.