Reward-related neural activity after low doses of LSD in participants with depressed mood

Although findings must be interpreted with caution, results support the idea that low doses of LSD have potential anti-depressant effects.

Authors

Robin Nusslock (ORCID: https://orcid.org/0000-0001-6283-7824)
James E. Glazer (ORCID: https://orcid.org/0000-0002-4682-2240)
Royce Lee
Hanna Molla
Harriet de Wit

Institutions

Northwestern University (US)
University of Chicago (US)

Publication Details

Journal: Journal of Psychopharmacology
Published: 2026-01-13
DOI: https://doi.org/10.1177/02698811251405686
Primary Topic: Psychedelics and Drug Studies
Type: article
Field-Weighted Citation Impact: 0.00

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article

Reward-related neural activity after low doses of LSD in participants with depressed mood

Robin Nusslock, James E. Glazer, Royce Lee, Hanna Molla et al.

Jan 13, 2026

Journal of Psychopharmacology

Psychedelics and Drug Studies

article

Reward-related neural activity after low doses of LSD in participants with depressed mood

Robin Nusslock, James E. Glazer, Royce Lee, Hanna Molla, Harriet de Wit

January 13, 2026article en

Abstract

Although findings must be interpreted with caution, results support the idea that low doses of LSD have potential anti-depressant effects.

Journal of Psychopharmacology

Northwestern University (US), University of Chicago (US)

Good health and well-being

Openalex Percentile: Top 90%

Psychedelics and Drug Studies

DOI Source OpenAlex

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Reward-related neural activity after low doses of LSD in participants with depressed mood — Robin Nusslock, James E. Glazer, et al. · Journal of Psychopharmacology (2026) | TGRS Research Map | TGRS