Dose-Volume Predictors of Fatal Bronchopulmonary Bleeding After Stereotactic Body Radiation Therapy of Centrally Located Lung Tumors: An Analysis of the Expanded HILUS Cohort
Bronchial tumor compression is a strong predictor for grade-5 bleeding, and the most relevant dose parameter appears to be the dose to a small volume of the main and intermediate bronchi.
Authors
- Britta Lödén
- Marianne Marquard Knap (ORCID: https://orcid.org/0000-0001-6215-8071)
- Ditte Sloth Møller (ORCID: https://orcid.org/0000-0001-9910-515X)
- Ingmar Lax
- Vitali Grozman
- Per Bergström (ORCID: https://orcid.org/0000-0003-3463-0249)
- Ninni Drugge
- Charlotte Kristiansen (ORCID: https://orcid.org/0000-0002-8073-5781)
- Hans-Olov Rosenbrand
- Elias Lindbäck
- Lotte Rogg
- Gitte Fredberg Persson (ORCID: https://orcid.org/0000-0002-3363-3256)
- Silke Engelholm
- Charlotte Billiet (ORCID: https://orcid.org/0000-0002-8483-850X)
- Karin Lindberg
- Sara Lindberg (ORCID: https://orcid.org/0000-0001-6634-4672)
- Eva Onjukka (ORCID: https://orcid.org/0000-0001-9113-4044)
- Tine Bjørn Nielsen (ORCID: https://orcid.org/0000-0003-1327-7837)
- Lotte Holm Land (ORCID: https://orcid.org/0000-0002-6208-7987)
- Jörgen Olofsson
- Tiziana Rancati
- Rebekka Knoph Hagen
- Karam Al-Jirf
- Christina Ramberg
- Anne-Sofie Frøland
- Jan Nyman
- Mirjana Josipovic
- Lone Hoffmann
- Kristin Karlsson
- André Haraldsson
- Azza Khalil
Institutions
- Oslo University Hospital (NO)
- Karolinska University Hospital (SE)
- University of Antwerp (BE)
- University of Southern Denmark (DK)
- Aarhus University (DK)
- Sahlgrenska University Hospital (SE)
- Odense University Hospital (DK)
- Aarhus University Hospital (DK)
- Copenhagen University Hospital (DK)
- Karolinska Institutet (SE)
- Vejle Sygehus (DK)
- University Hospital of Umeå (SE)
- Karlstad Central Hospital (SE)
- Iridium Kankernetwerk (BE)
- Skåne University Hospital (SE)
- Fondazione IRCCS Istituto Nazionale dei Tumori (IT)
Publication Details
- Journal
- International Journal of Radiation Oncology*Biology*Physics
- Published
- 2026-01-14
- DOI
- https://doi.org/10.1016/j.ijrobp.2025.12.007
- Primary Topic
- Lung Cancer Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00