Single-cell transcriptome sequencing revealing the microenvironment of breast fibroepithelial tumor
Our findings reveal molecular features that may underlie the rapid growth of juvenile giant fibroepithelial tumors. The data point to hormone-independent proliferative programs and immune-modulating fibroblast subtypes as key contributors. These insights broaden our understanding of tumor biology and may guide the development of targeted, less invasive treatments for young patients.
Authors
- Rong Guo (ORCID: https://orcid.org/0000-0003-3203-614X)
- Xuan Yang
- Cong Jiang (ORCID: https://orcid.org/0000-0002-6436-4386)
- Shicong Tang
- Min Zhao
- Shengnan Ren
- Jing Wang
- Ying Song
- Dechun Yang
- Fuying Yang
- Yafeng Lv
- Tianrun Shu
- Hanhui Xie
Institutions
- Kunming Medical University (CN)
- Red Cross Hospital (GR)
Publication Details
- Journal
- Biochemistry and Biophysics Reports
- Published
- 2026-01-14
- DOI
- https://doi.org/10.1016/j.bbrep.2026.102448
- Primary Topic
- Breast Lesions and Carcinomas
- Type
- article
- Field-Weighted Citation Impact
- 0.00