αA-Crystallin Attenuates Retinal Ischemia-Reperfusion Injury

Exogenous CRYAA mitigates retinal I/R injury by activating the Nrf2/HO-1 axis, reducing oxidative stress, and inhibiting apoptosis. These findings highlight CRYAA's therapeutic potential for ischemic retinal disorders and underscore Nrf2 as a critical mediator of its protective effects.

Authors

Huihang Wang (ORCID: https://orcid.org/0000-0003-3865-4272)
Y ZHU

Institutions

Fujian Medical University (CN)
First Affiliated Hospital of Fujian Medical University (CN)

Publication Details

Journal: Current Eye Research
Published: 2026-01-13
DOI: https://doi.org/10.1080/02713683.2026.2615658
Primary Topic: Retinal Development and Disorders
Type: article
Field-Weighted Citation Impact: 0.00

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article

αA-Crystallin Attenuates Retinal Ischemia-Reperfusion Injury

Huihang Wang, Y ZHU

Jan 13, 2026

Current Eye Research

Retinal Development and Disorders

article

αA-Crystallin Attenuates Retinal Ischemia-Reperfusion Injury

Huihang Wang, Y ZHU

January 13, 2026article en

Abstract

Current Eye Research

Fujian Medical University (CN), First Affiliated Hospital of Fujian Medical University (CN)

Good health and well-being

Openalex Percentile: Top 89%

Retinal Development and Disorders

DOI Source OpenAlex

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αA-Crystallin Attenuates Retinal Ischemia-Reperfusion Injury — Huihang Wang, Y ZHU · Current Eye Research (2026) | TGRS Research Map | TGRS