Atrial fibrillation is associated with increased in-hospital mortality and complications after IV t-PA in acute ischemic stroke: evidence from the China Stroke Center Alliance (CSCA)

The study highlights that having a past of AF is linked to a higher chance of cerebral hemorrhage and in-hospital mortality in Chinese AIS patients following IVT. AF history is a strong predictor of in-hospital mortality (AUC = 0.85).

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Publication Details

Journal
Frontiers in Neurology
Published
2026-01-14
DOI
https://doi.org/10.3389/fneur.2025.1667855
Primary Topic
Acute Ischemic Stroke Management
Type
article
Field-Weighted Citation Impact
0.00
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article

Atrial fibrillation is associated with increased in-hospital mortality and complications after IV t-PA in acute ischemic stroke: evidence from the China Stroke Center Alliance (CSCA)

Tianhao Zhang, R. Liu, Hanye Yuan, Liwen Xie et al.
Frontiers in Neurology
Acute Ischemic Stroke Management
article

Atrial fibrillation is associated with increased in-hospital mortality and complications after IV t-PA in acute ischemic stroke: evidence from the China Stroke Center Alliance (CSCA)

Tianhao Zhang, R. Liu, Hanye Yuan, Liwen Xie, Minghui Du, Zhigang Liang, Kaixuan Yang, Zhuqing Luan, Zhongwen Sun
article en

Abstract

The study highlights that having a past of AF is linked to a higher chance of cerebral hemorrhage and in-hospital mortality in Chinese AIS patients following IVT. AF history is a strong predictor of in-hospital mortality (AUC = 0.85).

Frontiers in NeurologyVol. 16
Binzhou Medical University (CN), Shandong University of Aeronautics (CN), Capital Medical University (CN), Yuhuangding Hospital (CN)
Good health and well-being
Openalex Percentile: Top 88%
Acute Ischemic Stroke Management
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Atrial fibrillation is associated with increased in-hospital mortality and complications after IV t-PA in acute ischemic stroke: evidence from the China Stroke Center Alliance (CSCA) — Tianhao Zhang, R. Liu, et al. · Frontiers in Neurology (2026) | TGRS Research Map | TGRS