Breast Adenoid Cystic Carcinoma: Recognizing a Rare Pathological Diagnosis

Adenoid cystic carcinoma (ACC) of the breast is an exceedingly rare neoplasm. It exhibits a distinct dual cell population and a favorable prognosis despite its often triple-negative immunophenotype. We present a rare case of ACC diagnosed on core needle biopsy and confirmed in the resection specimen. The histopathological features, immunohistochemical profile, and relevant literature are discussed. This case emphasizes the importance of recognizing this rare entity when encountered in breast biopsies and the necessity for a collaborative, multidisciplinary approach to management.

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Publication Details

Journal
Cureus
Published
2026-01-13
DOI
https://doi.org/10.7759/cureus.101447
Primary Topic
Salivary Gland Tumors Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Breast Adenoid Cystic Carcinoma: Recognizing a Rare Pathological Diagnosis

Shital Parekh, Prajakta Attarde
Cureus
Salivary Gland Tumors Diagnosis and Treatment
article

Breast Adenoid Cystic Carcinoma: Recognizing a Rare Pathological Diagnosis

Shital Parekh, Prajakta Attarde
article en

Abstract

Adenoid cystic carcinoma (ACC) of the breast is an exceedingly rare neoplasm. It exhibits a distinct dual cell population and a favorable prognosis despite its often triple-negative immunophenotype. We present a rare case of ACC diagnosed on core needle biopsy and confirmed in the resection specimen. The histopathological features, immunohistochemical profile, and relevant literature are discussed. This case emphasizes the importance of recognizing this rare entity when encountered in breast biopsies and the necessity for a collaborative, multidisciplinary approach to management.

CureusVol. 18(1)
Milton Keynes Hospital (GB)
Openalex Percentile: Top 89%
Salivary Gland Tumors Diagnosis and Treatment
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