GC-MS-based metabolic profiling of essential oils from Citrus paradisi, Lawsonia inermis, and Ruta graveolens and assessment of their acetylcholinesterase inhibitory potential
The notable AChE inhibitory activity observed in grapefruit and henna essential oils is likely attributable to their high terpenoid content. These findings suggest that selected plant-derived essential oils may represent promising natural candidates for the prevention or management of neurodegenerative disorders such as Alzheimer's disease.
Authors
- Naglaa S. Ashmawy (ORCID: https://orcid.org/0000-0002-5396-5901)
- Rema M. Amawi
Institutions
- Ain Shams University (EG)
- Rochester Institute of Technology (US)
- Dubai Medical College (AE)
- Dubai Pharmacy College (AE)
Publication Details
- Journal
- Frontiers in Chemistry
- Published
- 2026-01-14
- DOI
- https://doi.org/10.3389/fchem.2025.1761973
- Primary Topic
- Cholinesterase and Neurodegenerative Diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00