Adjunctive Systemic Amoxicillin and Metronidazole Following Surgical Peri‐Implantitis Treatment: A Single‐Blind Randomised Controlled Trial With a 1‐Year Follow‐Up

Access-flap peri-implantitis surgery supplemented with systemic amoxicillin and metronidazole led to a statistically significant reduction in peri-implant BOP after 1 year, whereas no other parameters showed statistically significant differences between groups at any timepoint. The clinical implications of these differences should be interpreted with caution, as the isolated short-term effect does not translate into broader or sustained clinical benefit and must be weighed against the risks associated with systemic antibiotic use.