Breast cancer microenvironment composition associated with high PD-L1 expression

High PD-L1 expression in BC tissue is associated with features of an immunosuppressive TME, including increased infiltration of immune cells with pro-tumorigenic properties, alterations in the cytokine profile, and remodeling of the stromal matrix.

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Publication Details

Journal
BMC Cancer
Published
2026-01-14
DOI
https://doi.org/10.1186/s12885-026-15542-0
Primary Topic
Cancer Immunotherapy and Biomarkers
Type
article
Field-Weighted Citation Impact
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article

Breast cancer microenvironment composition associated with high PD-L1 expression

Taras Zadvornyi, Т. Л. Бурда, Oleksandr Mushii, В Ф Чехун et al.
BMC Cancer
Cancer Immunotherapy and Biomarkers
article

Breast cancer microenvironment composition associated with high PD-L1 expression

Taras Zadvornyi, Т. Л. Бурда, Oleksandr Mushii, В Ф Чехун, V. BAZAS, Nataliia Iurevna Lukianova, Yelyzaveta Lukianova, Anna Pavlova, Iryna Shepelenko
article en

Abstract

High PD-L1 expression in BC tissue is associated with features of an immunosuppressive TME, including increased infiltration of immune cells with pro-tumorigenic properties, alterations in the cytokine profile, and remodeling of the stromal matrix.

BMC CancerVol. 26(1)
R.E. Kavetsky Institute of Experimental Pathology, Oncology and Radiobiology (UA), Kyiv City Clinical Oncology Center (UA)
Good health and well-being
Openalex Percentile: Top 88%
Cancer Immunotherapy and Biomarkers
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