Primary angioplasty/stenting versus mechanical thrombectomy as the initial approach for underlying ICAD-LVO: a multicenter retrospective cohort study

In this multicenter retrospective cohort study, primary angioplasty/stenting was associated with superior clinical efficacy compared to mechanical thrombectomy as the initial approach for underlying ICAD-LVO. This approach showed higher rates of 90-day functional independence while maintaining a comparable safety profile. These findings support the concept of etiology-specific endovascular strategies; however, this approach requires confirmation in prospective randomized controlled trials.