Failure patterns and clinical indications in early-stage follicular lymphoma: a study from the National Cancer Center in China

Patients with early-stage FL in this 20-year real-world Chinese cohort demonstrated an overall favorable long-term prognosis across diverse initial management strategies. No treatment modality showed a clear survival advantage in this limited-size cohort, while relapse was uncommon and more frequently locoregional than systemic. POD24 identified a small subset of patients with inferior survival, highlighting the need for individualized, risk-adapted management and long-term follow-up.

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Publication Details

Journal
Frontiers in Pharmacology
Published
2026-01-14
DOI
https://doi.org/10.3389/fphar.2026.1745000
Primary Topic
Lymphoma Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Failure patterns and clinical indications in early-stage follicular lymphoma: a study from the National Cancer Center in China

Shijie Yang, T. Wu, Chunqiang Xu, J. Jin et al.
Frontiers in Pharmacology
Lymphoma Diagnosis and Treatment
article

Failure patterns and clinical indications in early-stage follicular lymphoma: a study from the National Cancer Center in China

Shijie Yang, T. Wu, Chunqiang Xu, J. Jin, Hao Jing, Wen-wen Zhang, Xin Liu, Yong Yang, Hui Fang, Yue Liu, Jingru Zhu, Yunpeng Wu, Yuan Tang, Shu-Lian Wang, Shu-Nan Qi, Ye-Xiong Li, Ning Li, Qiu-Zi Zhong, Ning-Ning Lu, Si-Ye Chen, Yong-Wen Song, Bo Chen, Yue-Ping Liu
article en

Abstract

Patients with early-stage FL in this 20-year real-world Chinese cohort demonstrated an overall favorable long-term prognosis across diverse initial management strategies. No treatment modality showed a clear survival advantage in this limited-size cohort, while relapse was uncommon and more frequently locoregional than systemic. POD24 identified a small subset of patients with inferior survival, highlighting the need for individualized, risk-adapted management and long-term follow-up.

Frontiers in PharmacologyVol. 17
Fujian Medical University (CN), Chinese Academy of Medical Sciences & Peking Union Medical College (CN), Beijing Geriatric Hospital (CN), Guizhou Cancer Hospital (CN), Affiliated Hospital of Guizhou Medical University (CN), Beijing Hospital (CN), National Clinical Research (US)
Openalex Percentile: Top 89%
Lymphoma Diagnosis and Treatment
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