A stage specific NETs-related signature in alcoholic steatohepatitis: from molecular subtyping to therapeutic vulnerabilities

FOS, MMP7, and CXCL6 constitute a clinically actionable signature capturing the stage-specific dynamics of NETs-driven inflammation in ASH. Beyond its diagnostic and stratifying utility, this signature highlights potential therapeutic avenues for clinical intervention.

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Publication Details

Journal
Frontiers in Immunology
Published
2026-01-14
DOI
https://doi.org/10.3389/fimmu.2025.1711388
Citations
1
Primary Topic
Neutrophil, Myeloperoxidase and Oxidative Mechanisms
Type
article
Field-Weighted Citation Impact
24.43
Controls
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article

A stage specific NETs-related signature in alcoholic steatohepatitis: from molecular subtyping to therapeutic vulnerabilities

Mingjiang Liu, Yuntao Bao, Zhiyong Lin, Wei Gao et al.
1 citations
Frontiers in Immunology
Neutrophil, Myeloperoxidase and Oxidative Mechanisms
24.43
article

A stage specific NETs-related signature in alcoholic steatohepatitis: from molecular subtyping to therapeutic vulnerabilities

Mingjiang Liu, Yuntao Bao, Zhiyong Lin, Wei Gao, Guangtao Ma, Yonglian Zeng, Shuiping Yu
article en
1 citations

Abstract

FOS, MMP7, and CXCL6 constitute a clinically actionable signature capturing the stage-specific dynamics of NETs-driven inflammation in ASH. Beyond its diagnostic and stratifying utility, this signature highlights potential therapeutic avenues for clinical intervention.

Frontiers in ImmunologyVol. 16
Guangxi Medical University (CN), First Affiliated Hospital of GuangXi Medical University (CN)
Good health and well-being
Openalex Percentile: Top 2%
Neutrophil, Myeloperoxidase and Oxidative Mechanisms
24.43
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