Integrative bioinformatic and experimental analysis reveals prognostic and immunological roles of MEX3 family genes in glioma
This study provides a comprehensive characterization of the MEX3 family in glioma, demonstrating their dysregulation, prognostic relevance, immune associations, and functional contributions to malignant phenotypes. Among them, MEX3D emerges as a particularly promising prognostic biomarker. These findings establish a foundation for future mechanistic and translational studies exploring MEX3 family members as potential biomarkers or therapeutic targets in glioma.
Authors
- Xuezhong Zhang
- Hui Shang
- Tingting Chu
- Kaihui Sha
Institutions
- Binzhou Medical University (CN)
- Shandong University of Aeronautics (CN)
- Wenzhou Medical University (CN)
- Shanxi Jincheng Anthracite Mining Group (China) (CN)
- Central Hospital of Zibo (CN)
- Dongyang People's Hospital (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2026-01-14
- DOI
- https://doi.org/10.3389/fimmu.2025.1654036
- Primary Topic
- Glioma Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00