Oxylipin Responses during the Yukon Arctic Ultra: The Longest and Coldest Ultramarathon in the World
YAU athletes exhibit a distinct lipidomic signature marked by persistently elevated anti-inflammatory oxylipins, likely reflecting a complex interplay between adipose tissue and skeletal muscle. Overall, the oxylipin shifts point to anti-inflammatory and thermogenic adaptations that support physiological resilience during physical, nutrient, and environmental stress in austere circumstances.
Authors
- Robert H. Coker (ORCID: https://orcid.org/0000-0002-1037-9339)
- Tseng Yu-Hua
- Mathias Steinach (ORCID: https://orcid.org/0000-0002-7457-4301)
- Tadataka Tsuji (ORCID: https://orcid.org/0000-0002-2837-8246)
- Adriane Schalt
- Juan J. Aristizabal‐Henao (ORCID: https://orcid.org/0000-0002-2085-2396)
- Melynda S. Coker (ORCID: https://orcid.org/0000-0002-9019-6216)
- R. Lucas Thomas
- Michael A Kiebish
- Camilla Kienest
Institutions
- Joslin Diabetes Center (US)
- University of Washington (US)
- Berlin Institute of Health at Charité - Universitätsmedizin Berlin (DE)
- Framingham State University (US)
- University of Montana (US)
- Charité - Universitätsmedizin Berlin (DE)
Publication Details
- Journal
- Military Medicine
- Published
- 2025-12-17
- DOI
- https://doi.org/10.1093/milmed/usaf622
- Primary Topic
- Exercise and Physiological Responses
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Institutes of Health
- U.S. Army
- National Institute of General Medical Sciences
- National Institute of Diabetes and Digestive and Kidney Diseases
- U.S. Army Medical Research and Development Command