Beneficial effects of SGLT1/2 and SGLT2 inhibitors on vaso-occlusive events and organ damage in sickle cell disease mice
Our findings suggest that DAPA and SOTA mitigate vaso-occlusive events in SCD, with SOTA providing superior benefits.
Authors
- Radka Bokorová (ORCID: https://orcid.org/0000-0002-7364-4275)
- Alireza Sargazi (ORCID: https://orcid.org/0000-0003-1937-6051)
- Jae-Sung Kim (ORCID: https://orcid.org/0000-0003-2312-3954)
- Tripti Kumari (ORCID: https://orcid.org/0000-0002-2638-0705)
- J. Cho
- Soi Jeong (ORCID: https://orcid.org/0000-0002-2381-3325)
- Janet S. Lee
- Bo-Ram Jin
- Carla Valenzuela Ripoll (ORCID: https://orcid.org/0000-0002-6177-5227)
- Babak Razani
- Young-Min Hyun
- Jingu Lee
- Atish Gheware
- Sana Saif Ur Rehman
Institutions
- University of Pittsburgh (US)
- Yonsei University (KR)
- Washington University in St. Louis (US)
- University of Pittsburgh Medical Center (US)
- John Cochran VA Medical Center (US)
Publication Details
- Journal
- Cardiovascular Research
- Published
- 2026-01-13
- DOI
- https://doi.org/10.1093/cvr/cvag003
- Citations
- 1
- Primary Topic
- Hemoglobinopathies and Related Disorders
- Type
- article
- Field-Weighted Citation Impact
- 36.93