NEIL1 suppresses ROS accumulation to promote temozolomide resistance and malignant progression in glioma cells

NEIL1 drives glioma malignancy and TMZ resistance by mitigating oxidative stress and DNA damage, highlighting its role as a promising target to overcome chemoresistance.

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Publication Details

Journal
Translational Oncology
Published
2026-01-13
DOI
https://doi.org/10.1016/j.tranon.2026.102667
Primary Topic
RNA regulation and disease
Type
article
Field-Weighted Citation Impact
0.00
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article

NEIL1 suppresses ROS accumulation to promote temozolomide resistance and malignant progression in glioma cells

Qingyue Yuan, Xianzhen Chen, Chenhao Fang, Shuo Li
Translational Oncology
RNA regulation and disease
article

NEIL1 suppresses ROS accumulation to promote temozolomide resistance and malignant progression in glioma cells

Qingyue Yuan, Xianzhen Chen, Chenhao Fang, Shuo Li
article en

Abstract

NEIL1 drives glioma malignancy and TMZ resistance by mitigating oxidative stress and DNA damage, highlighting its role as a promising target to overcome chemoresistance.

Translational OncologyVol. 65
Tongji University (CN), Shanghai Tenth People's Hospital (CN)
Zero hunger
Openalex Percentile: Top 89%
RNA regulation and disease
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NEIL1 suppresses ROS accumulation to promote temozolomide resistance and malignant progression in glioma cells — Qingyue Yuan, Xianzhen Chen, et al. · Translational Oncology (2026) | TGRS Research Map | TGRS