Changes in body water distribution and phase angle following rapid ascent to 3,680 m and their association with acute mountain sickness: a prospective cohort study
After rapid exposure to high altitude, body water often shifted into cells and pronounced cellular-level dysfunction occurred. Susceptible individuals with AMS exhibited a more pronounced decrease in PhA. The change of PhA (ΔPhA), rather than the change of ECW/ICW (ΔECW/ICW), was an independent predictor of AMS severity. Monitoring ΔPhA may provide an effective, non-invasive method for early risk warning of AMS.
Authors
- Xianglian LI
- Yue Cheng (ORCID: https://orcid.org/0000-0002-8790-8649)
- Jun Zhang (ORCID: https://orcid.org/0000-0001-7886-6187)
- Liwen Mo
- Yanlin Zhu
- Yaru Li
- Jie He
Institutions
- Chinese General Hospital College of Nursing and Liberal Arts (PH)
- Southwest Jiaotong University (CN)
Publication Details
- Journal
- Frontiers in Public Health
- Published
- 2026-01-14
- DOI
- https://doi.org/10.3389/fpubh.2025.1742613
- Primary Topic
- High Altitude and Hypoxia
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Natural Science Foundation of Sichuan Province