Using sentinel surveillance system data to characterize severe malaria illness and quality of malaria case management among hospitalized patients in Kenya, 2017–2024
Modifiable factors that suggested delayed care-seeking were associated with worse malaria outcomes in Kenya. Furthermore, gaps in diagnostic accuracy and adherence to treatment protocols for severe malaria were observed during chart review. These findings point to the importance of behaviour change strategies as well as messaging in the community that promote timely care-seeking, referrals and follow-up, especially for the youngest children. Potential malaria over-diagnosis underscores the need for strengthening quality assured microscopy programs with adequate training of microscopists and properly functioning microscopes and reagents, as well as an external quality assurance programme that routinely provide feedback on performance and identify areas for improvement.
Authors
- Megumi Itoh (ORCID: https://orcid.org/0000-0002-9382-8960)
- Jonathan Schultz (ORCID: https://orcid.org/0000-0001-9405-5333)
- Peninah Munyua (ORCID: https://orcid.org/0000-0003-1950-8616)
- Mildred Shieshia
- George O. Agogo (ORCID: https://orcid.org/0000-0002-7685-7743)
- Steve Akoth (ORCID: https://orcid.org/0009-0004-9749-121X)
- Duncan Chege
- Naomi W. Lucchi (ORCID: https://orcid.org/0000-0001-8789-8041)
- Jonas Z. Hines (ORCID: https://orcid.org/0000-0002-4877-0333)
- Victor Sumbi
- Regina Kandie
- Doris Naitore Mwenda
- Edwin Oluoch Onyango
Institutions
- U.S. President's Malaria Initiative (US)
- Ministry of Health (KE)
- National Center for Emerging and Zoonotic Infectious Diseases (US)
- Centers for Disease Control and Prevention (KE)
- Division of Parasitic Diseases and Malaria (US)
Publication Details
- Journal
- Malaria Journal
- Published
- 2026-01-14
- DOI
- https://doi.org/10.1186/s12936-025-05738-3
- Primary Topic
- Malaria Research and Control
- Type
- article
- Field-Weighted Citation Impact
- 0.00