Vitamin D supplementation and selected metabolic parameters in patients with type 2 diabetes and obesity: a prospective observational study
High-dose vitamin D3 supplementation significantly improved vitamin D status and was associated with modest improvements in glycemic control in obese patients with T2DM, without affecting blood pressure, calcium, or body weight. These findings support vitamin D repletion as a potential adjunctive strategy in diabetes management, while not allowing causal inference, and warrant further confirmation in randomized controlled trials with longer follow-up.
Authors
- Shakta Mani Satyam (ORCID: https://orcid.org/0000-0001-5761-2073)
- Sorina Ispas (ORCID: https://orcid.org/0009-0000-3401-1232)
- Adil Farooq Wali (ORCID: https://orcid.org/0000-0003-1555-2820)
- Anna Paczkowska (ORCID: https://orcid.org/0000-0002-0058-2632)
- Syed Arman Rabbani (ORCID: https://orcid.org/0000-0002-8454-8158)
- Bhoomendra A. Bhongade (ORCID: https://orcid.org/0000-0002-4057-7125)
- Manfredi Rizzo (ORCID: https://orcid.org/0000-0002-9549-8504)
- Walaa Ibraheem (ORCID: https://orcid.org/0000-0003-4484-9367)
- Wiesław Bryl (ORCID: https://orcid.org/0000-0003-0135-409X)
- Ashot Avagimyan (ORCID: https://orcid.org/0000-0002-5383-8355)
- Mohamed El‐Tanani (ORCID: https://orcid.org/0000-0002-4735-5445)
- Karolina Hoffmann
- Viviana Maggio (ORCID: https://orcid.org/0009-0006-2211-8482)
- Imran Rashid Rangraze
- ILIAS IOANNIS
- Sirajunisa Talath
Institutions
- Poznan University of Medical Sciences (PL)
- Ovidius University (RO)
- University of Palermo (AR)
- Hippocration General Hospital (GR)
- Yerevan State Medical University (AM)
- Ras al-Khaimah Medical and Health Sciences University (AE)
Publication Details
- Journal
- Frontiers in Endocrinology
- Published
- 2026-01-14
- DOI
- https://doi.org/10.3389/fendo.2025.1750040
- Primary Topic
- Vitamin D Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00