Diagnostic whole transcriptome sequencing in a series of 1233 FFPE solid tumor samples
WTS is a reliable and informative method for fusion and splice variant detection in clinical diagnostics, provided rigorous pre-analytical and sequencing QC metrics are strictly applied.
Authors
- Petros Christopoulos (ORCID: https://orcid.org/0000-0002-7966-8980)
- AL Volckmar
- Christiane Zgorzelski
- Susanne Beck (ORCID: https://orcid.org/0000-0002-2652-8722)
- Iordanis Ourailidis (ORCID: https://orcid.org/0000-0001-6783-5617)
- Michael Menzel
- Markus Ball (ORCID: https://orcid.org/0000-0002-2312-8360)
- Regine Brandt
- Thoas Fioretos (ORCID: https://orcid.org/0000-0002-3235-6154)
- Huriye Seker‐Cin
- Alejandro Pallares Robles (ORCID: https://orcid.org/0000-0003-0352-4179)
- M. Kirchner
- Darius Wlochowitz
- Jan Budczies (ORCID: https://orcid.org/0000-0002-6668-5327)
- Fabian Schnecko
- Olaf Neuman
- Michael Thomas (ORCID: https://orcid.org/0000-0001-9511-055X)
- Katja Lorenz
- Annette Fink
- Hannah Goldschmid
- Tina Fuchs
- Michael Allgäuer
- Peter Schirmacher
- Solange Peters
- Daniel Kazdal
- Albrecht Stenzinger
Institutions
- German Cancer Research Center (DE)
- Lund University (SE)
- Heidelberg University (DE)
- University Hospital Heidelberg (DE)
- German Center for Lung Research (DE)
- Heidelberg Institute for Stem Cell Technology and Experimental Medicine (DE)
- Thorax Foundation (GR)
- Deutsches Konsortium für Translationale Krebsforschung (DE)
- University of Lausanne (CH)
Publication Details
- Journal
- British Journal of Cancer
- Published
- 2026-01-13
- DOI
- https://doi.org/10.1038/s41416-025-03307-8
- Primary Topic
- Cancer Genomics and Diagnostics
- Type
- article
- Field-Weighted Citation Impact
- 0.00