Platelets/lymphocytes ratio and neutrophils/lymphocytes ratio in children with H. pylori associated gastritis: a canary in the mine?

Low-grade systemic inflammation and localized stomach inflammation are both brought on by Helicobacter pylori (H. pylori), which is a prevalent cause of chronic gastritis. Recent adult studies reported that there is an association between H. pylori infection and both platelets/lymphocytes ratio (PLR) and neutrophils/lymphocytes (NLR) ratio. This study aimed to assess the association between H pylori positivity, severity, and both PLR and NLR ratios in children. We found that H. pylori-positive patients have considerably higher NLR and PLR. Moreover, PLR and NLR were good predictors for the presence and severity of H. infection in children with upper gastrointestinal tract symptoms.