Enhancing online adaptive radiotherapy with uncertainty based segmentation error and out-of-distribution detection

Uncertainty estimation from a DL-based segmentation model was seen to correlate with Dice scores for segmentation of MR-guided radiotherapy prostate cancer images. This implies that uncertainty estimation could be used to label the quality of the segmentations in the online adaptive radiotherapy workflow. Preliminary results showed that uncertainty estimation could be used to distinguish between ID and OOD data.

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Publication Details

Journal
Frontiers in Oncology
Published
2026-01-14
DOI
https://doi.org/10.3389/fonc.2025.1637198
Primary Topic
Advanced Radiotherapy Techniques
Type
article
Field-Weighted Citation Impact
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Enhancing online adaptive radiotherapy with uncertainty based segmentation error and out-of-distribution detection

Samuel Fransson, David Tilly, Robin Viktor Strand, Marissa van Lente et al.
Frontiers in Oncology
Advanced Radiotherapy Techniques
article

Enhancing online adaptive radiotherapy with uncertainty based segmentation error and out-of-distribution detection

Samuel Fransson, David Tilly, Robin Viktor Strand, Marissa van Lente, Josien Pluim
article en

Abstract

Uncertainty estimation from a DL-based segmentation model was seen to correlate with Dice scores for segmentation of MR-guided radiotherapy prostate cancer images. This implies that uncertainty estimation could be used to label the quality of the segmentations in the online adaptive radiotherapy workflow. Preliminary results showed that uncertainty estimation could be used to distinguish between ID and OOD data.

Frontiers in OncologyVol. 15
Uppsala University (SE), Information Technology University (PK), Uppsala University Hospital (SE), Radboud University Nijmegen (NL), University Medical Center (US), Radboud University Medical Center (NL), Eindhoven University of Technology (NL)
Openalex Percentile: Top 89%
Advanced Radiotherapy Techniques
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