Circulating CD34 <sup>+</sup> Fibroblast Progenitors Engaged in Heart Fibrosis of Allograft
We identify circulating CD34<sup>+</sup> cells as a novel source of fibroblast progenitors that contribute to cardiac allograft fibrosis, suggesting that targeting recipient CD34<sup>+</sup> cells could be a novel therapeutic potential for treating cardiac fibrosis after heart transplantation.
Authors
- Weishi Li (ORCID: https://orcid.org/0000-0001-9512-5436)
- H J Zhao
- Peng Teng (ORCID: https://orcid.org/0000-0001-7517-8442)
- Liang Ma (ORCID: https://orcid.org/0000-0001-9131-4512)
- Mengjia Chen
- Yichao Qiu
- Rong Mou
- Ting Wang
- Ting Chen
- Hui Gong
- Li Zhang
- Xiaogang Guo
- Wei Mao
- Jianing Xue
- Guoguo Ye
- Qingbo Xu
- Xiaotong Sun
Institutions
- Zhejiang Chinese Medical University (CN)
- X-Fab (Germany) (DE)
- XinHua Hospital (CN)
- Interface (United States) (US)
- First Affiliated Hospital Zhejiang University (CN)
- Alibaba Group (China) (CN)
Publication Details
- Journal
- Circulation Research
- Published
- 2026-01-14
- DOI
- https://doi.org/10.1161/circresaha.125.326558
- Primary Topic
- Transplantation: Methods and Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 0.00