Diffusion Spectrum Imaging Maps Early Axonal Loss and a Unique Progressive Signal in Neuronal Intranuclear Inclusion Disease
Our DSI framework resolves distinct pathological processes in NIID: QA serves as a biomarker for early detection, GFA maps to symptom heterogeneity, and ISO tracks disease progression, collectively advancing the pathophysiological model and clinical assessment of NIID.
Authors
- Yixiu Pei
- Kaiyan Jiang
- Xiaobao Hu
- Min Zhu (ORCID: https://orcid.org/0000-0002-9364-0810)
- Yang Li (ORCID: https://orcid.org/0000-0002-6515-4567)
- Dandan Tan (ORCID: https://orcid.org/0000-0002-1899-5988)
- Meihong Zhou
- Yanyan Yu (ORCID: https://orcid.org/0000-0002-7366-5826)
- Daojun Hong
- Fuqing Zhou
- Ying Xiong
Institutions
- Nanchang University (CN)
- Ganzhou People's Hospital (CN)
- First Affiliated Hospital of Nanchang University (CN)
Publication Details
- Journal
- Annals of Clinical and Translational Neurology
- Published
- 2026-01-12
- DOI
- https://doi.org/10.1002/acn3.70319
- Primary Topic
- Advanced Neuroimaging Techniques and Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Jiangxi Province
- Recruitment Program of Global Experts