Microtubule affinity-regulating kinase 4 exacerbates diabetic cardiomyopathy by inhibiting UNC-51-like kinase 1-mediated mitochondrial autophagy
Downregulation of MARK4 in DCM mice can reduce myocardial injury, protect mitochondrial function, and promote mitophagy by upregulating UNC-51-like kinase 1, protecting against cardiac damage.
Authors
- N. D. Qi (ORCID: https://orcid.org/0000-0003-0670-292X)
- Lu Fu
- Sai Wang
- Bin Li
- Yi Wu
- Zhi Zeng
- Wei-Yi Wang
Institutions
- Harbin Medical University (CN)
- Xianning Central Hospital (CN)
- First Affiliated Hospital of Harbin Medical University (CN)
Publication Details
- Journal
- World Journal of Diabetes
- Published
- 2026-01-14
- DOI
- https://doi.org/10.4239/wjd.v17.i1.112027
- Primary Topic
- Autophagy in Disease and Therapy
- Type
- article
- Field-Weighted Citation Impact
- 0.00