Erianin protects chondrocytes against IL-1β-induced oxidative stress and ferroptosis by activating GPX4/STING signaling in osteoarthritis
Eri demonstrates promising therapeutic potential in the treatment of OA by inhibiting chondrocyte ferroptosis and protecting against ECM degradation and inflammatory responses.
Authors
- Chao Fang
- Yun Wang
- Wei Jian
- Shuai Lu
- Cuiyu Li
Institutions
- Tongji University (CN)
- University of Science and Technology of China (CN)
- Chinese PLA General Hospital (CN)
- Xian Central Hospital (CN)
Publication Details
- Journal
- Inflammation Research
- Published
- 2026-01-14
- DOI
- https://doi.org/10.1007/s00011-025-02162-w
- Primary Topic
- Ferroptosis and cancer prognosis
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- University of Science and Technology of China