Astrocyte Activation in the Hippocampus Following Cardiopulmonary Bypass in a Rat Model: A Pilot Study

CPB induced astrocyte activation in the hippocampal CA3 region. These findings indicate that CPB induces astrocyte activation in the hippocampus, consistent with a neuroinflammatory response.

Authors

Kenji Yoshitani (ORCID: https://orcid.org/0000-0002-9161-0028)
Yusuke Nakano
Hiroya Tsujimoto
Ayami Shinomiya
Takahiro Tadokoro
Ryo Misawa

Institutions

National Cerebral and Cardiovascular Center (JP)

Publication Details

Journal: Cureus
Published: 2026-01-13
DOI: https://doi.org/10.7759/cureus.101465
Primary Topic: Neuroinflammation and Neurodegeneration Mechanisms
Type: article
Field-Weighted Citation Impact: 0.00

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article

Astrocyte Activation in the Hippocampus Following Cardiopulmonary Bypass in a Rat Model: A Pilot Study

Kenji Yoshitani, Yusuke Nakano, Hiroya Tsujimoto, Ayami Shinomiya et al.

Jan 13, 2026

Cureus

Neuroinflammation and Neurodegeneration Mechanisms

article

Astrocyte Activation in the Hippocampus Following Cardiopulmonary Bypass in a Rat Model: A Pilot Study

Kenji Yoshitani, Yusuke Nakano, Hiroya Tsujimoto, Ayami Shinomiya, Takahiro Tadokoro, Ryo Misawa

January 13, 2026article en

Abstract

CPB induced astrocyte activation in the hippocampal CA3 region. These findings indicate that CPB induces astrocyte activation in the hippocampus, consistent with a neuroinflammatory response.

CureusVol. 18(1)

National Cerebral and Cardiovascular Center (JP)

Good health and well-being

Openalex Percentile: Top 90%

Neuroinflammation and Neurodegeneration Mechanisms

DOI Open Access PDF OpenAlex

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Astrocyte Activation in the Hippocampus Following Cardiopulmonary Bypass in a Rat Model: A Pilot Study — Kenji Yoshitani, Yusuke Nakano, et al. · Cureus (2026) | TGRS Research Map | TGRS