Interpretable machine learning models for beta thalassemia prediction: an explainable AI approach for smart healthcare 5.0
Furthermore ensuring the models transparency and interpretability, the proposed method integrates SHapley Ad-ditive exPlanations (SHAP) and Local Interpretable Model-Agnostic Explanations (LIME), enabling both global and local interpretability of model predictions. SHAP gives us insight into important features at the global level, while LIME explains individual predictions, making the model's decisions more comprehensible for clinical applications.
Authors
- Abdul Hannan Khan
- Asaad Algarni (ORCID: https://orcid.org/0000-0002-0817-5775)
- Raheem Sarwar (ORCID: https://orcid.org/0000-0002-0640-807X)
- Muhammad Bilal Shoaib Khan
- Anas Bilal
- Maria Abbas
Institutions
- Northern Border University (SA)
- Manchester Metropolitan University (GB)
- Hainan Normal University (CN)
- Green University of Bangladesh (BD)
- Green Chemistry (PL)
Publication Details
- Journal
- Frontiers in Medicine
- Published
- 2026-01-14
- DOI
- https://doi.org/10.3389/fmed.2025.1688645
- Primary Topic
- Hemoglobinopathies and Related Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Northern Border University