Serum P2X7 as a prognostic biomarker in acute supratentorial intracerebral hemorrhage: a two-center observational study

Increased serum P2X7 levels after ICH are markedly associated with disease severity and poor prognosis. Moreover, P2X7 may partially mediate the relationship between ICH severity and prognosis, underscoring its potential as a prognostic biomarker.

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Publication Details

Journal
Frontiers in Neurology
Published
2026-01-14
DOI
https://doi.org/10.3389/fneur.2025.1696189
Primary Topic
Intracerebral and Subarachnoid Hemorrhage Research
Type
article
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article

Serum P2X7 as a prognostic biomarker in acute supratentorial intracerebral hemorrhage: a two-center observational study

Xiulin Dong, Guozheng Ying, Hao Shan, Xinle Chen et al.
Frontiers in Neurology
Intracerebral and Subarachnoid Hemorrhage Research
article

Serum P2X7 as a prognostic biomarker in acute supratentorial intracerebral hemorrhage: a two-center observational study

Xiulin Dong, Guozheng Ying, Hao Shan, Xinle Chen, Xiaojun Zhong, Tiancheng Lu, Yulin Sun, Boren Zheng
article en

Abstract

Increased serum P2X7 levels after ICH are markedly associated with disease severity and poor prognosis. Moreover, P2X7 may partially mediate the relationship between ICH severity and prognosis, underscoring its potential as a prognostic biomarker.

Frontiers in NeurologyVol. 16
Zhejiang Chinese Medical University (CN), Zhejiang Hospital (CN), Affiliated Hangzhou First People's Hospital, Westlake University, School of Medicine (CN)
No poverty
Openalex Percentile: Top 89%
Intracerebral and Subarachnoid Hemorrhage Research
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