Inflammatory burden in dialysis patients: the role of alpha defensin

HD is an alpha-defensin generating procedure. Patients are potentially predisposed to atherosclerosis because of their enhanced alpha defensin secretion. alpha-defensin might evolve as a potential therapeutic target for atherosclerosis mitigation in this high-risk population. However, this remains to be validated in future research.

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Publication Details

Journal
Frontiers in Immunology
Published
2026-01-14
DOI
https://doi.org/10.3389/fimmu.2025.1718452
Primary Topic
Antimicrobial Peptides and Activities
Type
article
Field-Weighted Citation Impact
0.00
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article

Inflammatory burden in dialysis patients: the role of alpha defensin

Rami Abu Fanne, Naama Amsalem, Adib Abo Aqil, Maanit Shapira et al.
Frontiers in Immunology
Antimicrobial Peptides and Activities
article

Inflammatory burden in dialysis patients: the role of alpha defensin

Rami Abu Fanne, Naama Amsalem, Adib Abo Aqil, Maanit Shapira, Isis Abumouch, Ameena Zahalka
article en

Abstract

HD is an alpha-defensin generating procedure. Patients are potentially predisposed to atherosclerosis because of their enhanced alpha defensin secretion. alpha-defensin might evolve as a potential therapeutic target for atherosclerosis mitigation in this high-risk population. However, this remains to be validated in future research.

Frontiers in ImmunologyVol. 16
Hillel Yaffe Medical Center (IL)
Good health and well-being
Openalex Percentile: Top 87%
Antimicrobial Peptides and Activities
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