Stereotactic Body Radiation Therapy for Pediatric, Adolescent, and Young Adult Patients With Osteosarcoma: Local Control Outcomes With Dosimetric Analysis

SBRT for recurrent/metastatic osteosarcoma is safe and effective, achieving a 13.6% 1-year LF rate. LFs were evenly distributed amongst in-field, marginal, and out-of-field. Spine SBRT had the highest LF risk, suggesting the need for tailored strategies near critical structures.

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Publication Details

Journal
Pediatric Blood & Cancer
Published
2026-01-14
DOI
https://doi.org/10.1002/1545-5017.70087
Primary Topic
Sarcoma Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Stereotactic Body Radiation Therapy for Pediatric, Adolescent, and Young Adult Patients With Osteosarcoma: Local Control Outcomes With Dosimetric Analysis

Zachary D. C. Burke, Jacob G. Scott, A. Magnelli, C.A. Reddy et al.
Pediatric Blood & Cancer
Sarcoma Diagnosis and Treatment
article

Stereotactic Body Radiation Therapy for Pediatric, Adolescent, and Young Adult Patients With Osteosarcoma: Local Control Outcomes With Dosimetric Analysis

Zachary D. C. Burke, Jacob G. Scott, A. Magnelli, C.A. Reddy, Eashwar Somasundaram, S. Campbell, Peter M. Anderson, Lukas M. Nystrom, Jonathan Jang, Erin S. Murphy, Matteo Trucco, Nathan Mesko, Jenna Kocsis, Lilyana Angelov
article en

Abstract

SBRT for recurrent/metastatic osteosarcoma is safe and effective, achieving a 13.6% 1-year LF rate. LFs were evenly distributed amongst in-field, marginal, and out-of-field. Spine SBRT had the highest LF risk, suggesting the need for tailored strategies near critical structures.

Pediatric Blood & CancerVol. 73(3)
Cleveland Clinic (US), Cleveland Clinic Lerner College of Medicine (US), Massachusetts General Hospital (US), The Ohio State University (US)
Good health and well-being
Openalex Percentile: Top 89%
Sarcoma Diagnosis and Treatment
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