Type 2 diabetes and age-related cognitive decline over 40 years in Danish men–A cohort study based on the Danish Aging and Cognition (DanACo) cohort

Type 2 diabetes was associated with modestly greater cognitive decline and higher odds of a statistically significant (>13.2 IQ points) and clinically relevant decline. Finally, the alignment between main and IPW results indicates the findings are robust and likely generalizable.

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Publication Details

Journal
PLoS ONE
Published
2026-01-13
DOI
https://doi.org/10.1371/journal.pone.0340622
Primary Topic
Dementia and Cognitive Impairment Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Type 2 diabetes and age-related cognitive decline over 40 years in Danish men–A cohort study based on the Danish Aging and Cognition (DanACo) cohort

Jørgen Rungby, Lonny Stokholm, Erik Lykke Mortensen, Marie Stjerne Grønkjær et al.
PLoS ONE
Dementia and Cognitive Impairment Research
article

Type 2 diabetes and age-related cognitive decline over 40 years in Danish men–A cohort study based on the Danish Aging and Cognition (DanACo) cohort

Jørgen Rungby, Lonny Stokholm, Erik Lykke Mortensen, Marie Stjerne Grønkjær, Merete Osler
article en

Abstract

Type 2 diabetes was associated with modestly greater cognitive decline and higher odds of a statistically significant (>13.2 IQ points) and clinically relevant decline. Finally, the alignment between main and IPW results indicates the findings are robust and likely generalizable.

PLoS ONEVol. 21(1)
University of Copenhagen (DK), Steno Diabetes Centers (DK), University of Southern Denmark (DK), Frederiksberg Hospital (DK), Copenhagen University Hospital (DK)
Quality Education
Openalex Percentile: Top 89%
Dementia and Cognitive Impairment Research
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