Teprotumumab associated menstrual changes

Menstrual changes occurred in 55% of menstruating females receiving teprotumumab therapy. The most common changes were amenorrhea and oligomenorrhea. The majority of patients regained normal menstruation after cessation of therapy. It is important for providers to be aware of this potential adverse event when treating menstruating women with TED.

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Publication Details

Journal
Orbit
Published
2026-01-13
DOI
https://doi.org/10.1080/01676830.2025.2609906
Primary Topic
Pregnancy and Medication Impact
Type
article
Field-Weighted Citation Impact
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article

Teprotumumab associated menstrual changes

Andrea L. Kossler, Patrick J. Hunt, Amina Malik, Karina Richani et al.
Orbit
Pregnancy and Medication Impact
article

Teprotumumab associated menstrual changes

Andrea L. Kossler, Patrick J. Hunt, Amina Malik, Karina Richani, Roman Shinder, Hila Goldberg, Cornelius Rosenbaum, Tracy Lu
article en

Abstract

Menstrual changes occurred in 55% of menstruating females receiving teprotumumab therapy. The most common changes were amenorrhea and oligomenorrhea. The majority of patients regained normal menstruation after cessation of therapy. It is important for providers to be aware of this potential adverse event when treating menstruating women with TED.

Orbit
Texas Medical Center (US), The University of Texas MD Anderson Cancer Center (US), SUNY Downstate Health Sciences University (US), Cornell University (US), American Society of Plastic Surgeons (US), Methodist Hospital (US), National Student Clearinghouse Research Center (US), Weill Cornell Medicine (US), Stanford University (US)
Good health and well-being
Openalex Percentile: Top 90%
Pregnancy and Medication Impact
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