Longitudinal analysis of metabolic changes in people with HIV on integrase inhibitor-based versus efavirenz-based therapy: a prospective real-world cohort study in China
INSTI-based ART was associated with sustained weight gain but did not worsen long-term dyslipidemia compared to an EFV-based regimen in a real-world setting. Hepatic steatosis correlated with metabolic parameters rather than INSTI exposure.
Authors
- Cai Sh
- Muye Xia
- Jie Peng (ORCID: https://orcid.org/0000-0002-4005-085X)
- Tao Yu (ORCID: https://orcid.org/0000-0003-1151-304X)
- Xuwen Xu (ORCID: https://orcid.org/0000-0002-6923-7319)
- Mingzhu Tao
- Bing Li
Institutions
- Nanfang Hospital (CN)
- Guangdong Provincial Center for Disease Control and Prevention (CN)
- Southern Medical University (CN)
Publication Details
- Journal
- BMC Infectious Diseases
- Published
- 2026-01-14
- DOI
- https://doi.org/10.1186/s12879-026-12553-x
- Primary Topic
- HIV-related health complications and treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00