Preformed <i>vs de novo</i> anti-human leukocyte antigens-DQ antibodies in kidney transplantation: A retrospective study
Our findings underscore the clinical significance of anti-HLA-DQ DSAs in Moroccan kidney transplant recipients. While preformed DSAs with low immunogenicity may permit successful transplantation, <i>de novo</i> DSAs strongly correlate with AMR. Proactive monitoring, including routine DSA screening and HLA-DQ typing, could improve graft outcomes by enabling early intervention and better donor selection.
Authors
- B. Ramdani
- G. Medkouri
- Majda Taoudi Benchekroun
- Mohammed Benghanem Gharbi (ORCID: https://orcid.org/0000-0003-2209-4071)
- Abdelhadi Cheggali
- Joumana El Turk
- Siham Bennani
- Oumaima Guissouss
- Asmaa Mourachid
- Khalid Achiaou
Institutions
- Université Internationale de Casablanca (MA)
- Centre Hospitalier Universitaire Ibn Rochd (MA)
- Institut Pasteur du Maroc (MA)
- University of Hassan II Casablanca (MA)
Publication Details
- Journal
- World Journal of Transplantation
- Published
- 2026-01-14
- DOI
- https://doi.org/10.5500/wjt.v16.i1.114044
- Primary Topic
- Renal Transplantation Outcomes and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00