Guillain–Barré syndrome following dengue infection in an adult patient: a case report

• Dengue infection can rarely trigger Guillain–Barré syndrome in adults • Early recognition of post-dengue GBS is critical in endemic regions • Timely IVIG and intensive care support can significantly improve outcomes Dengue fever is a viral disease that presents with a wide range of neurological features. Although less frequent, Guillain–Barré Syndrome (GBS) is a life-threatening, postinfectious neurological sequela. A 44-year-old Bangladeshi male presented with flaccid quadriplegia during the recovery phase of serologically confirmed dengue fever. Cerebrospinal fluid (CSF) analysis showed albuminocytologic dissociation. The patient was treated with intravenous immunoglobulin therapy and supportive measures, including mechanical ventilation. His condition improved after 14 days of critical care. This case underscores the importance of maintaining a high index of suspicion for GBS in patients with dengue fever in endemic regions. Early diagnosis and multidisciplinary management are essential for better outcomes.

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Publication Details

Journal
Brain Disorders
Published
2026-01-13
DOI
https://doi.org/10.1016/j.dscb.2026.100306
Primary Topic
Mosquito-borne diseases and control
Type
article
Field-Weighted Citation Impact
0.00
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article

Guillain–Barré syndrome following dengue infection in an adult patient: a case report

Risala Ahmed, Chowdhury Adnan Sami, Mohammad Mahfuzur Rahman, Nikhat Shahla Afsar et al.
Brain Disorders
Mosquito-borne diseases and control
article

Guillain–Barré syndrome following dengue infection in an adult patient: a case report

Risala Ahmed, Chowdhury Adnan Sami, Mohammad Mahfuzur Rahman, Nikhat Shahla Afsar, Sumaiya Farah Marisa, Nishat Ali, Sayat Quayum Mohona, Mehadi Hasan, Anika Shahidullah, Md. Imrul Hasan
article en

Abstract

• Dengue infection can rarely trigger Guillain–Barré syndrome in adults • Early recognition of post-dengue GBS is critical in endemic regions • Timely IVIG and intensive care support can significantly improve outcomes Dengue fever is a viral disease that presents with a wide range of neurological features. Although less frequent, Guillain–Barré Syndrome (GBS) is a life-threatening, postinfectious neurological sequela. A 44-year-old Bangladeshi male presented with flaccid quadriplegia during the recovery phase of serologically confirmed dengue fever. Cerebrospinal fluid (CSF) analysis showed albuminocytologic dissociation. The patient was treated with intravenous immunoglobulin therapy and supportive measures, including mechanical ventilation. His condition improved after 14 days of critical care. This case underscores the importance of maintaining a high index of suspicion for GBS in patients with dengue fever in endemic regions. Early diagnosis and multidisciplinary management are essential for better outcomes.

Brain DisordersVol. 21
Square Hospitals (BD)
Good health and well-being
Openalex Percentile: Top 90%
Mosquito-borne diseases and control
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Guillain–Barré syndrome following dengue infection in an adult patient: a case report — Risala Ahmed, Chowdhury Adnan Sami, et al. · Brain Disorders (2026) | TGRS Research Map | TGRS