Automation in value-based laboratory medicine: driving precision, capacity, and better outcomes

Laboratory medicine lies at the core of modern healthcare, enabling timely diagnosis, effective patient monitoring, and increasingly personalized therapeutic strategies. Over the past decades, automation has profoundly reshaped the role of clinical laboratories, substantially enhancing their contribution to clinical outcomes, operational efficiency, and the overall sustainability of healthcare systems. More recently, laboratory automation has emerged as a cornerstone of value-based laboratory medicine, representing not merely a technological upgrade but a strategic transformation of laboratory practice aimed at delivering measurable value to patients and healthcare stakeholders. Although automation has long been established in clinical chemistry and immunoassays, its scope is now expanding to molecular diagnostics and mass spectrometry - two disciplines that are central to precision medicine. Looking ahead, the convergence of automation, digitalization, and artificial intelligence is driving the emergence of hyperautomation in laboratory medicine. Within this paradigm, laboratories evolve from isolated testing units into integrated diagnostic hubs, in which results from multiple laboratory disciplines are harmonized and contextualized to effectively support clinical decision-making.

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Publication Details

Journal
Clinical Chemistry and Laboratory Medicine (CCLM)
Published
2026-01-14
DOI
https://doi.org/10.1515/cclm-2026-0023
Primary Topic
Clinical Laboratory Practices and Quality Control
Type
article
Field-Weighted Citation Impact
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article

Automation in value-based laboratory medicine: driving precision, capacity, and better outcomes

T Zima, D. Gruson, Mario Plebani
Clinical Chemistry and Laboratory Medicine (CCLM)
Clinical Laboratory Practices and Quality Control
article

Automation in value-based laboratory medicine: driving precision, capacity, and better outcomes

T Zima, D. Gruson, Mario Plebani
article en

Abstract

Laboratory medicine lies at the core of modern healthcare, enabling timely diagnosis, effective patient monitoring, and increasingly personalized therapeutic strategies. Over the past decades, automation has profoundly reshaped the role of clinical laboratories, substantially enhancing their contribution to clinical outcomes, operational efficiency, and the overall sustainability of healthcare systems. More recently, laboratory automation has emerged as a cornerstone of value-based laboratory medicine, representing not merely a technological upgrade but a strategic transformation of laboratory practice aimed at delivering measurable value to patients and healthcare stakeholders. Although automation has long been established in clinical chemistry and immunoassays, its scope is now expanding to molecular diagnostics and mass spectrometry - two disciplines that are central to precision medicine. Looking ahead, the convergence of automation, digitalization, and artificial intelligence is driving the emergence of hyperautomation in laboratory medicine. Within this paradigm, laboratories evolve from isolated testing units into integrated diagnostic hubs, in which results from multiple laboratory disciplines are harmonized and contextualized to effectively support clinical decision-making.

Clinical Chemistry and Laboratory Medicine (CCLM)
Cliniques Universitaires Saint-Luc (BE), University of Padua (IT), Charles University (CZ), General University Hospital in Prague (CZ), UCLouvain (BE)
Openalex Percentile: Top 90%
Clinical Laboratory Practices and Quality Control
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Automation in value-based laboratory medicine: driving precision, capacity, and better outcomes — T Zima, D. Gruson, et al. · Clinical Chemistry and Laboratory Medicine (CCLM) (2026) | TGRS Research Map | TGRS