Inflammation mediates the association between the Prognosis Nutrition Index (PNI) and mortality in acute pancreatitis: evidence from international cohorts
PNI is an independent determinant of mortality in AP, offering complementary prognostic value to BISAP. SIRS partially mediates this association but is not the primary pathway.
Authors
- Lingwei Huang
- Juan Liao (ORCID: https://orcid.org/0000-0002-9751-2752)
- Meimei Yang (ORCID: https://orcid.org/0000-0003-2498-2769)
- Lingjie Yan
- Fei He
- Dan Xiao
Institutions
- Sichuan University (CN)
- West China Hospital of Sichuan University (CN)
- The Affiliated Yongchuan Hospital of Chongqing Medical University (CN)
- Chongqing Emergency Medical Center (CN)
- Chongqing Medical University (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2026-01-14
- DOI
- https://doi.org/10.3389/fimmu.2025.1693888
- Primary Topic
- Pancreatitis Pathology and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00