Integrative analysis of EMT-driving genes identifies a prognostic signature and GJB2 as a potential biomarker in glioblastoma
Our findings provide a clinically applicable EMT-based prognostic framework that links transcriptional plasticity to patient outcomes in GBM and identify GJB2 as a promising therapeutic target.
Authors
- Junyan He (ORCID: https://orcid.org/0000-0002-8334-3484)
- Duo Gong
- B Y Wang
- X. Zeng (ORCID: https://orcid.org/0000-0002-1911-9162)
- Xiaofei Liu (ORCID: https://orcid.org/0009-0002-7232-2183)
- Wen-tao Xiao
- Min Zhou
Institutions
- Nantong University (CN)
- Affiliated Hospital of Nantong University (CN)
- First Affiliated Hospital of University of South China (CN)
- University of South China (CN)
Publication Details
- Journal
- Frontiers in Cell and Developmental Biology
- Published
- 2026-01-14
- DOI
- https://doi.org/10.3389/fcell.2025.1754988
- Primary Topic
- Glioma Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China