Case Report: Pathological confirmation and aggressive postoperative recurrence of WHO grade III rhabdoid meningioma

Rhabdoid meningioma (RM), a rare WHO grade III meningioma subtype, features high invasiveness, poor prognosis, and no effective therapies, often being misdiagnosed with other intracranial tumors clinically, such as brain metastases and WHO grade II meningiomas. We report a 39-year-old female admitted for 6-month headaches. Brain magnetic resonance imaging showed a well-circumscribed, heterogeneously enhancing tumor with severe peritumoral edema in the right temporal lobe, initially suspected to be a WHO grade II meningioma; RM was confirmed postoperatively. The tumor recurred 1 month after the first surgery, and the patient died of intracranial hypertension 1 month after the reoperation. This case highlights the need for immediate adjuvant chemoradiotherapy postoperatively.

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Publication Details

Journal
Frontiers in Medicine
Published
2026-01-14
DOI
https://doi.org/10.3389/fmed.2025.1715197
Primary Topic
Meningioma and schwannoma management
Type
article
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article

Case Report: Pathological confirmation and aggressive postoperative recurrence of WHO grade III rhabdoid meningioma

Z. Wang, YongJun Gao, Pengyan Guo, Wei Wang et al.
Frontiers in Medicine
Meningioma and schwannoma management
article

Case Report: Pathological confirmation and aggressive postoperative recurrence of WHO grade III rhabdoid meningioma

Z. Wang, YongJun Gao, Pengyan Guo, Wei Wang, Yongchao Gao, Pengyu Qiao, Rui Xu, Kun Lian
article en

Abstract

Rhabdoid meningioma (RM), a rare WHO grade III meningioma subtype, features high invasiveness, poor prognosis, and no effective therapies, often being misdiagnosed with other intracranial tumors clinically, such as brain metastases and WHO grade II meningiomas. We report a 39-year-old female admitted for 6-month headaches. Brain magnetic resonance imaging showed a well-circumscribed, heterogeneously enhancing tumor with severe peritumoral edema in the right temporal lobe, initially suspected to be a WHO grade II meningioma; RM was confirmed postoperatively. The tumor recurred 1 month after the first surgery, and the patient died of intracranial hypertension 1 month after the reoperation. This case highlights the need for immediate adjuvant chemoradiotherapy postoperatively.

Frontiers in MedicineVol. 12
Kunming Medical University (CN), The Sixth People's Hospital of Shenyang (CN)
No poverty
Openalex Percentile: Top 89%
Meningioma and schwannoma management
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