Congenital Neonatal Synchronous Triple and Dual Neural Tube Defects with Thoracolumbar, Lumbar and Sacral Myelomeningoceles: Two Case Reports

Abstract This manuscript describes two exceptionally rare neonatal presentations of synchronous multiple neural tube defects (NTDs), involving separate thoracolumbar, lumbar, and sacral myelomeningoceles. We report two neonates presenting with synchronous dual and triple, open and closed spinal dysraphisms—distributed across thoracolumbar, lumbar, and sacral regions— without associated cranial defects. Both infants underwent early surgical repair. Case 1 demonstrated favorable early neurological outcomes, while Case 2 exhibited persistent lower‑limb weakness and neurogenic bladder.