Dihydrolipoic acid suppresses ferroptosis in chondrocytes to ameliorate the progression of osteoarthritis by modulating the FOXO1/TXNIP signaling pathway
DHLA inhibits chondrocytes ferroptosis to alleviate OA progression through the FOXO1/TXNIP signaling pathway, offering a potential treatment strategy for OA.
Authors
- Zhenzhong Chen (ORCID: https://orcid.org/0000-0002-7882-1066)
- Y Chen
- Z Zhou
- Haiwei Ma (ORCID: https://orcid.org/0000-0002-6621-9131)
- Feijun Liu
- Yahong Lu
- Yu Bai
- Jiawei Fang
- Shijie Liu
- Dengwei He
- Hehuan Lai
- XingYu Hu
Institutions
- Lishui Central Hospital (CN)
Publication Details
- Journal
- Free Radical Biology and Medicine
- Published
- 2026-01-13
- DOI
- https://doi.org/10.1016/j.freeradbiomed.2026.01.021
- Primary Topic
- Ferroptosis and cancer prognosis
- Type
- article
- Field-Weighted Citation Impact
- 0.00