Identification of iron metabolism-related key genes and exploration of their potential mechanisms in hemophagocytic lymphohistiocytosis based on transcriptome sequencing
This study identified five validated key genes-ALOX15, CAT, HBZ, MT2A, and CYGB-offering new insights into HLH pathogenesis and potential therapeutic targets.
Authors
- Li Fen (ORCID: https://orcid.org/0000-0003-4173-0328)
- Yu Lin N.A.
- Jie Zhao (ORCID: https://orcid.org/0000-0002-9205-684X)
- Duan Hua Nan
- Gu Xue Zhong
Institutions
- First People's Hospital of Yunnan Province (CN)
- Yunnan Provincial Hospital of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- Frontiers in Medicine
- Published
- 2026-01-14
- DOI
- https://doi.org/10.3389/fmed.2025.1685793
- Primary Topic
- Autoimmune and Inflammatory Disorders Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00