A novel anoikis resistance-associated gene model for prognostic prediction and immune microenvironment characterization in lung squamous cell carcinoma

This validated ARG-based prognostic model effectively predicts survival outcomes and revealed strong associations between anoikis resistance, immune landscape alterations, and immunotherapy response, offering a framework for risk stratification and precision immunotherapy in LUSC clinical management.

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Publication Details

Journal
Discover Oncology
Published
2026-01-13
DOI
https://doi.org/10.1007/s12672-026-04395-5
Primary Topic
Ferroptosis and cancer prognosis
Type
article
Field-Weighted Citation Impact
0.00
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article

A novel anoikis resistance-associated gene model for prognostic prediction and immune microenvironment characterization in lung squamous cell carcinoma

Dong Ou, Hui Wang, Daishun Liu, Yi Liu et al.
Discover Oncology
Ferroptosis and cancer prognosis
article

A novel anoikis resistance-associated gene model for prognostic prediction and immune microenvironment characterization in lung squamous cell carcinoma

Dong Ou, Hui Wang, Daishun Liu, Yi Liu, Jin Nie
article en

Abstract

This validated ARG-based prognostic model effectively predicts survival outcomes and revealed strong associations between anoikis resistance, immune landscape alterations, and immunotherapy response, offering a framework for risk stratification and precision immunotherapy in LUSC clinical management.

Discover OncologyVol. 17(1)
Guizhou University (CN), Zunyi Medical University (CN), First People’s Hospital of Zunyi (CN), People's Hospital of Bishan District (CN), Guizhou Provincial People's Hospital (CN), Affiliated Hospital of Zunyi Medical College (CN), Chongqing Medical University (CN)
Openalex Percentile: Top 90%
Ferroptosis and cancer prognosis
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A novel anoikis resistance-associated gene model for prognostic prediction and immune microenvironment characterization in lung squamous cell carcinoma — Dong Ou, Hui Wang, et al. · Discover Oncology (2026) | TGRS Research Map | TGRS