Prevalence and prognostic value of baseline and post-treatment renal insufficiency in colorectal cancer patients: a large retrospective cohort study of 10,581 patients in Shanghai, China (2019–2023)
These results demonstrate that comprehensive RI assessment (incorporating eGFR, hematuria, proteinuria, and other RI-related parameters) provides clinically actionable insights. Given the high prevalence (baseline RI 32.4%, PTRI 20.3%) and significant survival impacts, early screening of RI and preventive strategies are critical for high-risk CRC patients.
Authors
- Baoshuai Liu
- Chen Bai (ORCID: https://orcid.org/0009-0000-7052-3745)
- Jian Lü (ORCID: https://orcid.org/0000-0002-9144-7486)
- Juan Li (ORCID: https://orcid.org/0000-0001-8320-2406)
- Shouyu Pan
- Guangwen Cao
- Xian Hua Gao
- Lianjie Liu
- Wei Zhang
- Jianjun Jiang
Institutions
- Naval Medical Research Command (US)
- Second Military Medical University (CN)
- Shenyang Anorectal Hospital (CN)
- Changhai Hospital (CN)
- International Hereditary Cancer Center (PL)
Publication Details
- Journal
- Frontiers in Medicine
- Published
- 2026-01-13
- DOI
- https://doi.org/10.3389/fmed.2025.1671990
- Primary Topic
- Chronic Kidney Disease and Diabetes
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Shanghai Municipal Health Commission
- National Natural Science Foundation of China
- Changhai Hospital of Shanghai
- National Key Research and Development Program of China