Hyperlactatemia, Coagulopathy, and Hepatic Injury as Prognostic Markers of Mortality in Pediatric Dengue: A Single-Center Retrospective Cohort Study

Hyperlactatemia, coagulopathy, and hepatocellular injury are significantly correlated with mortality in dengue, with lactate and PT-INR demonstrating particularly robust individual discriminative capabilities. These readily available biomarkers may help identify high‑risk patients early, but the proposed cutoffs require prospective multicenter validation before routine integration into dengue management protocols.